Cst smad3
WebPolyclonal Antibody for studying Smad3. Cited in 177 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in-house, Smad3 Antibody (CST #9513) is ready to ship. WebOct 2, 2024 · However, the importance of TGF-β-Smad2/3 signaling in fibroblast-mediated cardiac fibrosis has not been directly evaluated in vivo. Here, we examined pressure overload-induced cardiac fibrosis in fibroblast- and myofibroblast-specific inducible Cre-expressing mouse lines with selective deletion of the TGF-β receptors Tgfbr1/2, Smad2, …
Cst smad3
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WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-Smad3 antibody [EP568Y] (ab40854) Research with confidence – consistent and reproducible results with every batch. Long-term and … Web960化工网为您提供TGF-β Antibody产品详细说明，厂家联系电话，及其相关产品，找TGF-β Antibody， 请联系美国CST中国，，电话： 021-58356288 上960化工网，全国免费电话4000-025-960
WebJan 25, 2024 · A pan acetylation antibody (9441S, CST) was used. H) KAT6A knockdown (KD) decreases the acetylation (Ac-Lys) of SMAD3 in MDA-MB-231 cells. I) Effect of acetyltransferase activity-deficient mutants G657E and C543G/G657E of KAT6A on SMAD3 acetylation. J) MS analysis of acetylation sites of SMAD3 by KAT6A. ... In addition, in … WebPhospho-Smad3 (Ser423/425) (C25A9) Rabbit mAb detects endogenous levels of Smad3 when phosphorylated at Ser423/425. This antibody does not cross-react with other family members. ... but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Antibody Performance Guarantee.
WebJul 5, 2024 · Pin1 depletion restored Smad3 protein levels and tumor-suppressive activity, suggesting that the Pin1-Smad3 interaction has a negative impact on canonical Smad3 action. Collectively, the data show that the Pin1-Smad3 interaction, facilitated by CDK-mediated Smad3 phosphorylation, is associated with oncogenic TGFβ signaling and … WebSmad2 (L16D3) Mouse mAb detects endogenous levels of total Smad2 protein and may detect Smad3 due to high sequence homology. Species Reactivity: Human, Mouse, Rat, Monkey. ... Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, …
Highly specific and rigorously validated in-house, Smad3 Antibody (CST #9513) is ready to ship. ... Smad2 and Smad3 become phosphorylated at their carboxyl termini (Ser465 and 467 on Smad2; Ser423 and 425 on Smad3) by TGF-β Receptor I. Phosphorylated Smad 2/3 can complex with Smad4, translocate to the nucleus and regulate gene expression (9-11
WebNov 30, 2024 · By contrast, the Smad3 protein level showed no significant change among the different groups (Fig. 5c). As a result, the promotion of MSC osteogenesis is mainly mediated by activation of the BMP2 ... sls health minnesotaWeb本发明所述多肽，可以有效结合子宫内膜癌细胞中异常增多的突变型tp53，抑制smad3的磷 酸化 和子宫内膜癌生长，从而降低放疗剂量以及 化疗药物 的使用浓度，提高子宫内膜癌细胞的 放化疗 敏感性，且对正常细胞无明显 副作用 。 sls heating and coolingWebSep 27, 2024 · The antibodies used for ChIP-qPCR were anti-SMAD3 (CST and C67H9), anti-SMAD4 (CST and D3R4N), and anti-USP7(Bethyl and A300-033A). All ChIP-qPCR primers are listed in Supplementary Table S1. sls healthWebMonoclonal Antibody for studying CD3epsilon. Cited in 9 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CD3ε (CD3-12) Rat Monoclonal Antibody (CST #4443) is ready to ship. sls health services texasWebNational Center for Biotechnology Information sls helocWebFeb 11, 2024 · 松果菊苷（上海融禾医药科技发展有限公司，纯度97%，批号：190906）；兔多克隆抗体TGF-β1（美国 Abcam 公司）；phospho-Smad2（p-Smad2,美国 CST 公司）；phospho-Smad3（p-Smad3, Bioss公司）；蛋白Marker（美国Thermo 公司）；Trizol 试剂（加拿大Roche 公司）；逆转录试剂盒（谷歌 ... sls health lawsuitWebApr 10, 2024 · TGF-beta 506 transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 507 and ERK/Sp1 signaling pathways. ... at 4°C overnight. All antibodies are purchased from Cell Signaling 717 Technology (CST, Danvers, MA, USA), except the EGFR antibody cocktail (Cat 718 No. AHR5062, RRID: … soia - beach oog in al