Ctgf lncrna
WebOct 7, 2024 · Finally, luciferase reporter assays showed that the 3'-end sequences of lncRNA H19 and CTGF contained the binding site of miR-19b. In conclusion, our study … WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN …
Ctgf lncrna
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WebApr 12, 2024 · Noncoding RNAs (ncRNAs) play fundamental roles in cardiac development and cardiovascular diseases (CVDs), which are a major cause of morbidity and mortality. With advances in RNA sequencing technology, the focus of recent research has transitioned from studies of specific candidates to whole transcriptome analyses. Thanks to these … WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, …
WebMar 10, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. CTGF regulates biological ... WebNov 7, 2024 · Connective-tissue growth factor (Ctgf), also known as cellular communication network 2 (Ccn2), is a candidate extracellular matrix (ECM) ... as Ctgf is …
WebApr 3, 2024 · Cui, Yue and Shi, Bozhong and Zhou, Zijie and Chen, Bo and Zhang, Xiaoyang and Li, Cong and Luo, Kai and Zhu, Zhongqun and Zheng, Jinghao and He, Xiaomin, LncRNA CFRL Aggravates Cardiac Fibrosis by Modulating Both miR-3113-5p/CTGF and miR-3473d/FN1 Axis. WebDec 12, 2024 · During the proliferative phase of diabetic wound healing, lncRNA H19 recruits the transcription factor SRF to the CTGF promoter region, activating CTGF and its downstream MAPK signaling pathway to accelerate fibroblast proliferation and wound healing. These findings elaborate lncRNA H19 as a regulator in the regenerative phase …
WebApr 23, 2024 · LncRNA PFAL was found to have profibrotic activity, which manifested itself upon the inhibition of miR-18a. ... (TGF-β1) and connective tissue growth factor (CTGF) …
WebSep 3, 2024 · Connective tissue growth factor (CTGF), also referred to as CCN2, belongs to the CCN (acronym for Cyr61, CTGF, ... The lncRNA AK139128 may be involved in this communication during IR, potentially as a regulator of cardiac remodeling. Other lncRNA have also been reported to participate in cardiac IR. tsa blitz youth footballWebMay 5, 2024 · This has been supported by expression of specific protein-coding genes that facilitate organ-specific metastatic tropism (such as connective tissue growth factor … phillis wheatley minneapolisWebThe etiology of polycystic ovary syndrome (PCOS) is complex and the pathogenesis is not fully understood. Some studies have shown that dysregulation of ovarian granulosa cells may be related to abnormal follicles and excessive androgen in women with PCOS. Our team has also confirmed the high expression status of H19 in PCOS patients in the early … phillis wheatley mom and dadWebJul 18, 2024 · Gene expression data analysis identified several genes, including Il6, Tgfb2, Cxcl1, Mmp13, Ctgf, Sost and lncRNA MALAT1, differentially regulated in co-cultures compared to monocultures. We also identified Sost as a regulator of MALAT1 in PC3 cells. phillis wheatley monumentWebSep 28, 2024 · The etiology of polycystic ovary syndrome (PCOS) is complex and the pathogenesis is not fully understood. Some studies … tsab my learningWebLncRNA MSTRG.15746 and Il6 as well as lncRNA MSTRG.74451 and Il1f9 may have trans-regulatory relationships . These results suggested that lncRNAs and their targeted genes might be associated with the protective effect of itaconate, indicating that the regulatory role of lncRNAs is an ideal entry point to study the mechanism by which … phillis wheatley most famous poemWebJan 8, 2024 · The TGFβ–ALK5 signaling axis can directly mediate inhibition of endothelial cell proliferation and migration (Fig. 5b). 160,161 Indirectly, the expression of some key angiogenic factors, such ... tsa blow dryer